It is found in the body in very small amounts and for only seconds at a time. People use dimethylglycine to make medicine. Dimethylglycine is used for attention deficit-hyperactivity disorder (ADHD), epilepsy, chronic fatigue syndrome (CFS), allergies, respiratory disorders, pain and swelling (inflammation), cancer, alcoholism, and drug addiction. DMG, which stands for Dimethylglycine, has been demonstrated through more than 40 years worth of clinical research to dramatically improve the nutritional environment of the cells, tissues and organs of the human body so you can function at more youthful levels no matter how old you are!
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| ECHA InfoCard | 100.002.201 |
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| Properties | |
| C4H8N2O2 | |
| Molar mass | 116.120 g·mol−1 |
| Appearance | White/Off White Powder |
| Density | 1.37 g/cm3 |
| Melting point | 240 to 241 °C (464 to 466 °F; 513 to 514 K) |
| Boiling point | decomposes |
| low | |
| Structure | |
| 0 | |
| Hazards | |
| Main hazards | Toxic, Skin/Eye Irritant |
| Safety data sheet | External MSDS |
| GHS pictograms | |
| GHS Signal word | Danger |
| H228, H301 | |
| P210, P240, P241, P264, P270, P280, P301+310, P321, P330, P370+378, P405, P501 | |
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| Related compounds | |
| Hydroxylamine salicylaldoxime | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| verify (what is ?) | |
| Infobox references | |
Dimethylglyoxime is a chemical compound described by the formula CH3C(NOH)C(NOH)CH3. Its abbreviation is dmgH2 for neutral form, and dmgH for anionic form, where H stands for hydrogen. This colourless solid is the dioxime derivative of the diketone butane-2,3-dione (also known as diacetyl). DmgH2 is used in the analysis of palladium or nickel. Its coordination complexes are of theoretical interest as models for enzymes and as catalysts. Many related ligands can be prepared from other diketones, e.g. benzil.
Preparation[edit]
Dimethylglyoxime can be prepared from butanone first by reaction with ethyl nitrite to give biacetyl monoxime. The second oxime is installed using sodium hydroxylamine monosulfonate:[1]
Complexes[edit]
Dimethylglyoxime is used to detect and quantify nickel, which forms the bright red complex nickel bis(dimethylglyoximate) (Ni(dmgH)2). The reaction was discovered by L. A. Chugaev in 1905.[2]
Cobalt complexes have also received much attention. In chloro(pyridine)cobaloxime[3] the macrocycle [dmgH]22− mimics the macrocyclic ligand found in vitamin B12.
References[edit]
- ^Semon, W. L.; Damerell, V. R. (1930). 'Dimethylglyoxime'. Organic Syntheses. 10: 22. doi:10.15227/orgsyn.010.0022.CS1 maint: multiple names: authors list (link)
- ^Lev Tschugaeff (1905). 'Über ein neues, empfindliches Reagens auf Nickel'. Berichte der Deutschen Chemischen Gesellschaft. 38 (3): 2520–2522. doi:10.1002/cber.19050380317.
- ^Girolami, G.. S.; Rauchfuss, T.B.; Angelici, R. J. (1999). Synthesis and Technique in Inorganic Chemistry: A Laboratory Manual (3rd ed.). pp. 213–215.
by Roger V. Kendall, Ph.D.
Dimethylglycine (DMG) is a relatively small molecule with an amazing power to change and improve health, well-being, and vitality in a person's life.
A natural substance found in certain foods like meat (liver), beans, seeds, and grains, DMG is an intermediary metabolite—meaning it is rapidly broken down into other useful substances your body requires. DMG, which affects many metabolic pathways within the cell, is also produced in small amounts by humans and animals. Officially named N, N-Dimethylglycine, DMG is related to the amino acid, glycine, whose two hydrogen atoms have been replaced with methyl (CH3) groups on its nitrogen atom. Research shows it to be physiologically active and important to cell metabolism, as well as a supplier of essential methyl groups for modifying, building, and detoxifying many components in the body.
Over 25 years of research and clinical studies have demonstrated DMG, as a nutritional supplement, has many positive effects, including stress reduction, improved athletic and sexual performance, and enhanced cardiovascular, brain, and immune functions. An adaptogen, DMG works with other co-factors in the body to counteract the negative effects of physical, emotional, and metabolic stress and to help prevent and overcome degenerative diseases. It can also normalize physiological functions and help maintain homeostasis (balance) within the body. These physiological functions include the regulation of blood glucose levels, immune response, blood pressure, hypoxic or low-oxygen conditions, hormone and cholesterol levels, as well as those of important biologically active molecules like SAMe, glutathione, and creatine.
Studies also show DMG:
- Provides useful building blocks for the biosynthesis of vitamins, hormones, neurotransmitters, antibodies, nucleic acids, and other metabolically active molecules
- Supports all aspects of immune response by acting as an anti-viral, anti-bacterial, and anti-fungal agent
- Promotes cardiovascular functions by supporting normal triglyceride and cholesterol levels, reducing angina, improving circulation, and decreasing elevated homocysteine levels
- Improves oxygenation, thus reducing fatigue and increasing energy for improved physical and mental performance
- Supports neurological function and mental clarity by acting as a precursor to the amino acids that are building blocks for neurotransmitters
- Acts as an antioxidant against free radicals
- Supports detoxification and enhances liver function, particularly Phase II detoxification (the phase that excretes converted toxic metabolites)